Pulmonary Arterial Hypertension

Pulmonary Arterial Hypertension eBook Free Download

Pulmonary Arterial Hypertension eBook PDF Free Download

Edited by Robyn J. Barst

Diagnosis and Evidence-Based Treatment

Published by Wiley

About the Book

This Pulmonary Arterial Hypertension is edited by Robyn J. Barst. This First Edition textbook dedicated to this disease previously thought to be incurable, but with the advent of new drugs, now amenable to management and a much-improved prognosis for patients.

From the PAH Association, the leading experts in the field. Incorporates the latest AACP management guidelines. Includes evidence-based treatment algorithms based on the recently updated ACCP Guidelines for Medical Treatment. Aimed at specialists in pulmonology and cardiovascular disease, this volume provides the clinician with the most up to date information on the effective management of PAH.

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What You Will Learn

The Topics Covered in this Textbook are

1. Introduction

2. Diagnosis and assessment of pulmonary arterial hypertension
2.1 Hemodynamics of pulmonary hypertension
2.2 Venice classification
2.3 Overview of the diagnostic process (algorithm)
2.4 Screening (identifying a pre-existing risk)
2.5 Detection (discovering pulmonary hypertension)
2.6 Definition (diagnosing the clinical context)
2.7 Prediction (estimating prognosis)
2.8 Principles of follow-up (evaluating and responding to outcome)
2.9 Specific tests in the evaluation of pulmonary hypertension

3. Conventional therapy in pulmonary arterial hypertension
3.1 Calcium channel antagonists
3.2 Diuretics
3.3 Warfarin
3.4 Supplemental oxygen
3.5 Inotropic therapy
3.6 General measures
3.7 Conclusions

4. Prostanoid treatment for pulmonary arterial hypertension
4.1 Epoprostenol
4.2 Treprostinil
4.3 Iloprost
4.4 Beraprost
4.5 Treatment selection
4.6 Conclusions

5. Endothelin receptor antagonists in pulmonary arterial hypertension
5.1 Bosentan
5.2 Sitaxsentan
5.3 Ambrisentan
5.4 Safety and tolerability with endothelin receptor antagonists
5.5 Conclusions

6. Phosphodiesterase-5 inhibitors in pulmonary arterial hypertension
6.1 The origins of phosphodiesterase-5 inhibitor development
6.2 Pulmonary hypertension as a new indication for phosphodiesterase-5 inhibitor treatment
6.3 Role of phosphodiesterase-5 in the pulmonary vasculature
6.4 Clinical experience with sildenafil for the treatment of chronic pulmonary hypertension
6.5 Pivotal trial and approval of sildenafil for the treatment of pulmonary arterial hypertension
6.6 Other phosphodiesterase-5 inhibitors
6.7 Combination therapy
6.8 Potential new indications for phosphodiesterase-5 inhibitors outside pulmonary arterial hypertension
6.9 Conclusions

7. Combination therapy for pulmonary arterial hypertension
7.1 Background
7.2 Combination therapy to date
7.3 Conclusions

8. Interventional and surgical modalities of treatment for pulmonary arterial hypertension
8.1 Introduction
8.2 Atrial septostomy
8.3 Pulmonary endarterectomy in chronic thromboembolic pulmonary hypertension
8.4 Lung transplantation for pulmonary hypertension
8.5 Conclusions

9. Endpoints and clinical trial design in pulmonary arterial hypertension: Clinical and regulatory perspectives
9.1 Introduction
9.2 Trial design
9.3 End points in trials of therapy for pulmonary arterial hypertension
9.4 Conclusions

10. Comparative analysis of clinical trials and evidence-based treatment algorithm for pulmonary arterial hypertension
10.1 Introduction
10.2 Randomized controlled studies
10.3 Long-term continuation studies
10.4 Combination studies
10.5 Evidence-based treatment algorithm
10.6 Conclusions

11. Diagnosis and assessment of non-pulmonary arterial hypertension masquerading as idiopathic pulmonary arterial hypertension: Diastolic heart failure – evaluation and interactions
11.1 Definition of heart failure
11.2 Epidemiology
11.3 Physiology
11.4 Evaluation of diastolic heart failure: Invasive and noninvasive techniques
11.5 Diagnosis and treatment of diastolic dysfunction
11.6 Pulmonary hypertension and diastolic dysfunction
11.7 Conclusions

12. Treatment of pulmonary arterial hypertension: A look to the future
12.1 Therapy of pulmonary arterial hypertension
12.2 Measuring outcomes and monitoring the course of therapy
12.3 Conclusions

For Whom is this Book For

This Pulmonary Arterial Hypertension: Diagnosis and Evidence-Based Treatment is perfect for Residents and Practicing Physicians. It is the must-have reference for practitioners and residents! It acts as Reference Material for those MBBS students who are pursuing their Post-Graduation in General Medicine. It includes topics pretty useful for Other Health Care Professionals including Clinical Pharmacists, Nurses and Professors.


Format of the eBook: PDF    Size: 12.2 MB




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