Immunotherapy for Gastrointestinal Cancer

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Immunotherapy for Gastrointestinal Cancer eBook Free Download

Immunotherapy for Gastrointestinal Cancer eBook PDF Free Download

Edited by David Kerr and Rebecca Johnson

Published by Springer

About the Book

This Immunotherapy for Gastrointestinal Cancer is edited by David Kerr and Rebecca Johnson. This First Edition is about the manipulation of the immune system as a therapeutic approach to gastrointestinal cancer and its clinical applications, exploring therapeutic approaches which might be taken under the broad banner of immunotherapy. Starting by introducing concepts of modern immunology, the clinical applications of immunotherapy are then discussed. The reader will learn about the three broad classes of immune therapeutic agents: cell-based treatment; antibody therapy; cytokine application and the key effector cells and mechanisms which might cause tumour rejection. The reverse side of this equation, the genetic and molecular mechanisms which the tumour can use to escape immune control and regulation, is also discussed. Through reviewing the most up-to-date evidence, this volume provides an overview of the important scientific lessons learned from past failure of immunotherapeutics in the clinic and highlights more positive recent data, coupled to practical guidelines for clinical usage. Written by a team of worldwide experts, this is an indispensable guide for medical oncologists, surgical oncologists, radiation therapists, pharmacists, oncology nurse specialists.

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What You will Learn

The Topics Covered in this Textbook are

Introduction to Modern Immunology
Cell Based Therapy: Modified Cancer Cells
Therapeutic Cancer Vaccines
Antibody Drug and Radionuclide Conjugates for GI Cancers
Antibodies that Inhibit Specific Cellular Pathways in Gastric Cancer
PD1 and PD-L1 Immune Checkpoint Inhibitors in Gastrointestinal Cancer
The Role of the JAK/STAT Signalling Pathway in Immunoregulation of Gastrointestinal Cancers
Hypermutated Colorectal Cancer and Neoantigen Load
Antibodies for Treatment of Metastatic Colorectal Cancer

For Whom is this Book For

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Details

Format of the eBook: PDF               Size: 4.6 MB

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Immunotherapy for Gastrointestinal Cancer eBook Free Download

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