Cytoskeleton of the Nervous System

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Cytoskeleton of the Nervous System eBook Free Download

Cytoskeleton of the Nervous System eBook PDF Free Download

Edited by Ralph A. Nixon and Aidong Yuan

Published by Springer

About the Book

This Cytoskeleton of the Nervous System is edited by Ralph A. Nixon and Aidong Yuan. This First Edition monograph begins with a general description of the cytoskeleton in axonal development and pathology and then moves to more detailed descriptions of particular components, including microtubules and associated proteins, neurofilaments and interacting proteins, actin and its binding proteins, and glial fibrillary acidic protein. The later chapters focus on the functional significance of the neuronal cytoskeleton in axonal transport and its regulation in health and disease states. The Cytoskeleton of the Nervous System will encourage further development of unifying principles and stimulate new conceptual and technical approaches toward a better understanding of cytoskeleton functions in health and disease.

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What You will Learn

The Topics Covered in this Textbook are

Central Axonal Development and Pathology in Early Life
Microtubules in the Nervous System
Tau Phosphorylation
Tau Pathology
Tauopathy and Brain Aging
Microtubule-Associated Protein
Structure of Neural Intermediate Filament
Alpha-Internexin: The Fourth Subunit of Neurofilaments in the Mature CNS
Peripherin Pathology
Neurofilament Cross-Bridge – A Structure Associated Specifically with the Neurofilament Among the Intermediate Filament Family
Neurofilament Transport
Knockout Models of Neurofilament Proteins
Neurofilaments and Radial Growth: Deconstruction of a Hypothesis Through the Construction of Gene Targeted Mice
Deregulation of Cytoskeletal Protein Phosphorylation and Neurodegeneration
Neurofilaments in Aged Animals
Neurofilament Changes in Multiple Sclerosis
Intermediate Filament Interactions in Neurons
Tropomyosins in Neuronal Morphogenesis and Development
The Driving Machinery for Growth Cone Navigation
Glial Fibrillary Acidic Protein: The Intermediate Filament Protein of Astrocytes
Axonal Transport Mechanisms in Cytoskeleton Formation and Regulation
Axonal Transport and Motor Neuron Disease
In Vivo Imaging of Axonal Transport in Aging and Alzheimer’s Disease
Regulation of Cytoskeletal Composition in Neurons: Transcriptional and Post transcriptional Control in Development, Regeneration, and Disease
Crosstalks Between Myelinating Cells and the Axonal Cytoskeleton
Topographic Regulation of Neuronal Intermediate Filament Proteins by Phosphorylation: In Health and Disease
Cytoskeleton, Axonal Transport, and the Mechanisms of Axonal Neuropathy
Effects of Insulin on Tau and Neurofilament
Ethanol Effects on the Cytoskeleton of Nerve Tissue Cells

For Whom is this Book For



Format of the eBook: PDF         Size: 14.4 MB


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