Collagenase in Dupuytren Disease

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Collagenase in Dupuytren Disease eBook Free Download

Collagenase in Dupuytren Disease eBook PDF Free Download

Edited by Giorgio Pajardi, Marie A. Badalamente and Lawrence C. Hurst

Published by Springer

About the Book

This Collagenase in Dupuytren Disease is edited by Giorgio Pajardi, Marie A. Badalamente and Lawrence C. Hurst. This First Edition offers detailed guidance on the use of collagenase, or enzymatic fasciotomy, as a nonsurgical treatment for Dupuytren’s contracture and explains its role in relation to the other forms of treatment, including open fasciectomy, needle aponeurotomy, and lipofilling. Clear guidance is provided on technique, current indications, and off-label usage. With the help of tips and tricks from leading experts, the reader will learn how to personalize the procedure to meet the needs of individual patients. Advice is also provided on all aspects of rehabilitation, which is a key determinant of treatment outcome. Collagenase treatment of Dupuytren’s disease has the benefits of low invasiveness and rapid patient recovery and achieves reasonable recurrence-free periods. It is especially valuable in patients with rapid recurrence following surgery. In documenting and appraising every aspect of its use, this book will be of value for all who treat patients with Dupuytren’s disease, including hand surgeons, orthopedists, plastic surgeons, physiatrists, and physiotherapists.

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What You will Learn

The Topics Covered in this Textbook are

Biochemistry and Mechanism of Action of Collagenase on Collagen
Collagenase: Preclinical Evaluation and Clinical Trials in the USA and Australia
The Normal Fibrous Skeleton of the Hand and Change in Dupuytren’s Contracture
Collagenase in Europe from the Experimental Phase to Practical Use
Preparation, Injection and Traction Procedures (Pearls and Tips and Tricks): Technical Evolution and Results in Severe Cases
Dupuytren’s Disease of the Thumb and First Web
Rehabilitation After Treatment
Follow-up Studies, Satisfaction, Recurrence, Dosage and Drug Safety
American and European Regulations
Collagenase: Future Perspectives

For Whom is this Book For



Format of the eBook: PDF         Size: 5.6 MB


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