Clinical Nephrotoxins, 3rd Edition

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Clinical Nephrotoxins, 3rd Edition eBook Free Download

Clinical Nephrotoxins 3rd Edition eBook PDF Free Download

Edited by Marc E. De Broe and George A. Porter

Renal Injury from Drugs and Chemicals

Published by Springer

About the Book

This Clinical Nephrotoxins: Renal Injury from Drugs and Chemicals, 3rd Edition is edited by Marc E. De Broe and George A. Porter. This Third Edition textbook is a comprehensive text on all aspects of adverse effects by drugs, chemical substances and radiation on the kidneys. The importance of the toxicity of drugs and other substances for the kidneys is increasingly recognized.

The book consists of themes such as clinical relevance, renal handling and cellular mechanisms of nephrotoxicity, as well as animal and cell culture models. In addition, the volume highlights specific types of drugs, such as anti-infectious agents and anti-inflammatory, cardiovascular and anti-cancer drugs.

The last section deals with prevention and focuses on urinary biomarkers, pharmacological aspects and drug dosage in renal failure. In this third and completely revised edition, several new topics were added and additional figures and tables will be included. The book is of interest for the nephrologist, internist, general practitioner, toxicologist, pharmacologist, anesthesiologist, epidemiologist, public health official, pharmaceutical industry, and national drug safety committees, among others.

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What You will Learn

The Topics Covered in this Textbook are

Clinical relevance
Drug-associated acute kidney injury in the intensive care unit
Renal handling of drugs and xenobiotics
Pharmacological aspects of nephrotoxicity
Pharmacovigilance: from signal to action
Urinary biomarkers and nephrotoxicity
Toxin-induced immunological renal disease
Cellular mechanisms of nephrotoxicity
Animal models for the assessment of acute renal dysfunction and injury
Renal cell culture models: Contribution to the understanding of nephrotoxic mechanisms
Use of dialytic therapies for poisoning
Aminoglycosides and vancomycin
Beta-lactam antibiotics
Amphotericin B
Sulfonamides, sulfadiazine, trimethoprim-sulfamethoxazole, pentamidine, pyrimethamine, dapsone, quinolones
Antiviral agents
Analgesics and 5-aminosalicylic acid
Non-steroidal anti-inflammatory drugs
Gold salts, D-penicillamine and allopurinol
Angiotensin I convert ing enzyme inhibitors and angiotensin II receptor antagonists
Diuretics and alcohol ingestion
Anticancer drugs
Anesthetic agents
Bisphosphonates and the kidney
Proton pump inhibitors: acute interstitial nephritis and other renal effects
Oral sodium phosphate bowel purgatives and acute phosphate nephropathy
Illicit drug abuse and renal disease
Nephrotoxicity of calcineurin and mTOR inhibitors
Immunomodulators: interleukins, interferons, and IV immunoglobulin
Imaging agents
Lithium-associated kidney effects
Herbal remedies containing aristolochic acid and mushroom nephrotoxicity
Lead nephropathy
Cadmium-induced renal effects
Mercury-induced renal effects
Organic solvents, silicon-containing compounds and pesticides
Balkan nephropathy
Nephrotoxins in Africa
Paraphenylene diamine hair dye poisoning
Trace metal disturbances in end-stage renal failure patients
Smoking and the kidney
Star fruit
Drug dosage in renal failure

For Whom is this Book For

This Clinical Nephrotoxins: Renal Injury from Drugs and Chemicals, 3rd Edition is perfect for Urologists, Residents and Practicing Physicians. It is the must have reference for practitioners and residents! It acts as Reference Material for those MBBS students who are pursuing their Post-Graduation in Urology and Nephrology. It includes topics pretty useful for Other Health Care Professionals including Clinical Pharmacists, Nurses and Professors.


Format of the eBook: PDF      Size: 22 MB


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