Chemotherapy for Leukemia

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Chemotherapy for Leukemia eBook Free Download

Chemotherapy for Leukemia eBook PDF Free Download

Edited by Takanori Ueda

Novel Drugs and Treatment

Published by Springer

About the Book

This Chemotherapy for Leukemia: Novel Drugs and Treatment is edited by Takanori Ueda. This First Edition focuses on the latest progress in chemotherapy for leukemia and related diseases, including still-ongoing but promising studies. The effectiveness of treatment for chronic myeloid leukemia and acute promyelocytic leukemia has been dramatically improved in recent years. This improvement has been made possible with the development of molecular targeted agents such as bcr-abl tyrosine kinase inhibitors and all-trans retinoic acid. The antibody for the unique target of chemokine receptor 4 for adult T-cell leukemia/lymphoma, or FLT3 inhibitors (signaling inhibitors) has been applied to other leukemias. Also, chemotherapeutic agents including antimetabolite analogues such as clofarabine, and azacitidine (an epigenetic regulator) have undergone progressive development. Meanwhile, the novel concept of therapy targeting leukemic stem cells has been developed. The contributors discuss prospective results of basic and preclinical studies and clinical possibilities based on the effects for leukemic stem cells. This work facilitates a comprehensive understanding of modern treatment methodology for leukemia. The volume therefore will greatly benefit not only hematologists but also oncologists, all physicians who specialize in blood cancer, and pharmacologists who are involved in the development of therapeutic agents for leukemia.

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What You will Learn

The Topics Covered in this Textbook are

An Overview
Imatinib: Basic Results
Imatinib: Clinical Pharmacology and Therapeutic Results
Dasatinib, Nilotinib, Bosutinib, Ponatinib, and Other TKIs
Rituximab and Alemtuzumab for Chronic Lymphocytic Leukemia: Basic Results and Pharmacokinetics
Rituximab and Alemtuzumab for Chronic Lymphocytic Leukemia: Clinical Pharmacology and Therapeutic Results
Inotuzumab Ozogamicin for Acute Lymphoblastic Leukemia: Clinical Pharmacology and Therapeutic Results
Blinatumomab for Acute Lymphoblastic Leukemia: Clinical Pharmacology and Therapeutic Results
Mogamulizumab in Adult T-Cell Leukemia/Lymphoma
FLT3 Inhibitors
Retinoic Acid, All-trans Retinoic Acid (ATRA), and Tamibarotene
The Molecular Basis of Arsenic Trioxide Treatment for Acute Promyelocytic Leukemia (APL)
Arsenic Trioxide: Clinical Pharmacology and Therapeutic Results
Nelarabine
Forodesine
Clofarabine: Structure, Mechanism of Action, and Clinical Pharmacology
Clinical Use of Clofarabine for Adults and Children with Leukemia
Re-emerging Antimetabolites with Novel Mechanism of Action with Respect to Epigenetic Regulation: Basic Aspects
Epigenetic Regulator, Re-emerging Antimetabolites with Novel Mechanism of Action (Azacitidine and Decitabine): Clinical Pharmacology and Therapeutic Results
Therapies Targeting Leukemic Stem Cells

For Whom is this Book For

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Details

Format of the eBook: PDF                 Size: 8 MB

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Chemotherapy for Leukemia eBook Free Download

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