Cardiac Electrophysiology Methods and Models

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Cardiac Electrophysiology Methods and Models eBook Free Download

Cardiac Electrophysiology Methods and Models eBook PDF Free Download

Edited by Daniel C. Sigg, Paul A. Laizzo, Yong-Fu Xiao and Bin He

Published by Springer

About the Book

This Cardiac Electrophysiology Methods and Models is edited by Daniel C. Sigg, Paul A. Laizzo, Yong-Fu Xiao and Bin He. This First Edition is the major cause of mortality and morbidity in the Western Hemisphere. While significant progress has been made in treating a major sub-category of cardiac disease, arrhythmias, significant unmet needs remain. In particular, every day, thousands of patients die because of arrhythmias in the US alone, and atrial fibrillation is the most common arrhythmia affecting millions of patients in the US alone at a given time. Therefore, there is a public need to continue to develop new and better therapies for arrhythmias. Accordingly, an ever increasing number of biomedical, pharmaceutical, and medical personnel is interested in studying various aspects of arrhythmias at a basic, translational, and applied level, both in industry (ie Biotech, Pharmaceutical and device), and in academia. Not only has our overall understanding of molecular bases of disease dramatically increased, but so has the number of available and emerging molecular, pharmacological or device treatment based therapies. This practical, state-of-the art handbook will summarize and review key research methods and protocols, their advantages and pitfalls, with a focus on practical implementation, and collaborative cross-functional research. The volume will include visual and easy-to-use graphics, bulleted summaries, boxed summary paragraphs, links to reference websites, equipment manufacturers where appropriate, photographs of typical experimental setups and so forth, to keep this book very focused on practical methods and implementation, and yet, provide enough theory that the principles are clearly understood and can be easily applied.

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What You will Learn

The Topics Covered in this Textbook are

Clinical Cardiac Electrophysiology: An Overview of Its Evolution
Basic Cardiac Electrophysiology: Excitable Membranes
Cardiac Action Potentials, Ion Channels, and Gap Junctions
Anatomy and Physiology of the Cardiac Conduction System
The Electrocardiogram and Clinical Cardiac Electrophysiology
Principles of Electrophysiological In Vitro Measurements
Cardiac Cellular Electrophysiological Modeling
Computer Modeling of Electrical Activation: From Cellular Dynamics to the Whole Heart
Detection and Measurement of Cardiac Ion Channels
Cell Culture Models and Methods
Isolated Tissue Models
Isolated Heart Models
Small Animal Models for Arrhythmia Studies
Use of Large Animal Models for Cardiac Electrophysiology Studies
Optical Mapping and Calcium Imaging
Electrophysiology of Single Cardiomyocytes: Patch Clamp and Other Recording Methods
Invasive Electroanatomical Mapping and Navigation
Cardiac Electrophysiological Imaging: Solving the Inverse Problem of Electrocardiography
Traditional Electrophysiological Mapping
Multi-channel System for Analysis of Cardiac Rhythmicity and Conductivity In Vitro
Cardiac CT/MRI Imaging for Electrophysiology
Introduction to Translational Research
Clinical Perspective: Electrophysiology in the Young and Patients with Congenital Heart Disease

For Whom is this Book For

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Details

Format of the eBook: PDF         Size: 18.54 MB

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