Asthma: Targeted Biological Therapies

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Asthma: Targeted Biological Therapies eBook Free Download

Asthma: Targeted Biological Therapies eBook PDF Free Download

Edited by Girolamo Pelaia, Alessandro Vatrella and Rosario Maselli

Published by Springer

About the Book

This Asthma: Targeted Biological Therapies is edited by Girolamo Pelaia, Alessandro Vatrella and Rosario Maselli. This First Edition focuses on the fundamentals of the use of biologics in asthma, describing the rationale, principles, mechanisms of action, and indications. It offers an excellent balance between basic science and the analysis of clinical trials, updating readers with new developments that are changing the global scenario for targeted biological anti-asthma therapies, especially with regard to more severe disease. A range of therapies are considered, from the humanized monoclonal anti-IgE antibody omalizumab, widely approved as add-on treatment for inadequately controlled disease, through to emerging biologics for which evidence supportive of efficacy is accumulating, including anti-IL-5, anti-IL-4, and anti-IL-13 therapies. One aspect to emerge is the variability in individual response, which suggests a need for characterization of different asthma subtypes to permit the effective implementation of phenotype-targeted treatments. This book will be of interest for pulmonologists, clinical immunologists, and physicians seeking sound information on these therapies, but also for scientists and pharmacologists wishing to enhance their knowledge of the therapeutic implications of the cellular and molecular mechanisms that underlie severe, uncontrolled asthma.

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What You will Learn

The Topics Covered in this Textbook are

Introduction
Inflammatory Cellular Patterns in Asthma
Airway Remodelling in Asthma
Anti-IgE Therapy
IL-5-Targeted Antibodies
Anti-IL-4/IL-13 Biologics
Anti-TNF-α Therapies
Biologic Treatments Targeted to Innate Cytokines
Other Biologic Drugs
Conclusions and Future Perspectives

For Whom is this Book For

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Details

Format of the eBook: PDF      Size: 2.4 MB

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Asthma: Targeted Biological Therapies eBook Free Download

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